Goodbye Ina

Ina Jaegy, one of our undergraduate researchers, is off to a new adventure in chemistry research. We will miss you Ina and we are so grateful for the work you have done on gonial cluster staging!

Jasmine wins honorable mention for Spector Prize in Biology

One of our undergraduate research students, Jasmine Sun, won an honorable mention for the 2025 Marion Smith Spector Prize in Biology. The prize recognizes academic excellence and outstanding undergraduate achievement in research.

Jasmine will join the lab as a DBCRM Postbac research assistant in August!

Congratulations for all your success Jasmine!

Goodbye Mia

Mia was a visiting undergraduate from Peru through a program called REPU. She spent about 3 months with us an now safely returned home. We will miss you Mia, and thank you for all your hardwork!

A case for broadening our view of mechanism in developmental biology

Mansi Srivastava, Swathi Arur, and Duygu wrote this opinion piece in Development, questioning the term “mechanism” in biology research (specifically dev bio) and calling people to broaden their perspective on mechanistic studies. We hope this article creates a healthy conversation that can result in being more open to diverse ways we approach research.

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Abstract: Developmental biologists can perform studies that describe a phenomenon (descriptive work) and/or explain how the phenomenon works (mechanistic work). There is a prevalent perception that molecular/genetic explanations achieved via perturbations of gene function are the primary means of advancing mechanistic knowledge. We believe this to be a limited perspective, one that does not effectively represent the breadth of work in our field. We surveyed a representative and diverse group of colleagues to share their views on what it takes to infer mechanism. Here, we briefly examine the factors that have shaped the dominant view of mechanism, summarize responses to the survey, present our views, and suggest a path forward that embraces a broad outlook on the diversity of studies that advance knowledge in our field.

Welcome new undergrads! Lucy and Zeynep

We have new undergrads! Lucy, a WashU 1st year student, joined the lab early in the fall. Zeynep, an exchange student from Türkiye, will be joining us in early 2025. Welcome both!

Cellular mechanisms of annelid regeneration - New paper!

We have a new publication in Nature Communications, a companion paper to our Pristina leidyi work published earlier this year! This was a part of Duygu’s postdoctoral work when she was back in Guillaume Balavoine’s lab in Paris. It is a great collaborative effort by several labs (Raible, Balavonie, Ruta) that culminated in a fantastic paper addressing some of the big questions in annelid regeneration. More here:

https://source.washu.edu/2024/11/understanding-the-mechanics-of-regeneration/

Skeet by the Raible Lab here: https://bsky.app/profile/tessmarraiblelabs.bsky.social/post/3lb7oy7fsnc2g

Tweet by the Balavoine Lab here: https://twitter.com/BalavoineLab/status/1858472829970256001

It's a worm's world: regeneration and regrowth in the Özpolat Lab

Article by Maddy Frank.

Inside a corner lab in the basement of Busch, thousands of worms lay in wait.

The windowless room stays at a cool 18 degrees Celsius. Small plastic containers (think the ones you might have put some craft supplies in as a kid) line the front wall, each a contained saltwater habitat where juvenile worms hide in tubes of their own creation.

It feels almost Marvel movie-esque—a multitude of worlds stacked on top of one another, where only a chosen few can see the full picture.

…. read the rest of the article here….

Platynereis dumerilii germ cell regeneration - New Publication!

We have a new publication in Developmental Biology!

Developmental stage dependent effects of posterior and germline regeneration on sexual maturation in Platynereis dumerilii

This is the hard work of Bria Metzger , who was a post-bac research assistant in our lab, now a graduate student at University of Washington in Seattle.

Here is a Twitter thread about this work.

And we will be on Developmental Biology’s cover with this photo taken by Ryan Null!

We will be at Euro-Evo-Devo in Finland

Exciting times, Duygu is one of the organizers of the Platynereis Satellite Meeting.

Ranny, Duygu, Ryan are giving talks at the satellite meeting.

Ranny is giving a talk at the Evo Devo main meeting. Duygu and Ryan have posters.

Come say hi if you’ll be there!

Welcome new undergrads and goodbye Lisa!

We send the undergrad Lisa Cheung who graduated this year off to her new adventures.

And we welcome 4 new undergrads: Adebimbola Adedeji, Alina Krawczynski, Ina Jaegy, and Solana Cariello. Welcome to the team!