Rannyele (Ranny) has joined us as a post-doctoral researcher, and will be working on establishing single cell sequencing techniques to investigate germline cell regeneration in Platynereis. Ranny is a Brazilian scientist passionate about annelids and she received her PhD from the Autonomous University of Madrid, Spain, where she worked on regeneration in syllid annelids.
Welcome Ranny!
Jamie MacKinnon joined the lab as a research assistant, and will be working on optimizing growth in Platynereis dumerilii cultures. Jamie has received her B.S. in Marine Biology from Roger Williams University.. Welcome Jamie!
(PS: Beets, bears, Battlestar Galactica)
Bria, Emma, and Duygu taught at the Embryology Course at the MBL this year. We thank all the students for their amazing work, great (and slightly crazy) ideas, and excitement around our lil worms!
Here are some pictures of the dapi and phalloidin stain on a worm we collected in Woods Hole by Mike and Marlen. (We called her Scary Lady, she is a Glyceridae species). Here are her pictures before fixing.
Bria will present a poster at the 80th SDB Meeting (virtual this year). Come check out her poster!
Program Abstract #390 and Remo Table #C11
Poster Session 3C
Session Date: Wednesday, July 14, 2021
Presentation Time: 1:30 PM - 2:45 PM EDT
Location: Remo Building C
We are happy to welcome Rebecca Bachtel, who joined the lab this summer as a research assistant. Rebecca has a master’s degree and studied invasive snails and their trematode parasites, which affect different bird species that ingest the snails. Rebecca will work on establishing transgenic lines of Platynereis at our lab.
We have a new society for regeneration! International Society for Regenerative Biology.
The society will have its first meeting in April. Duygu will be giving a talk on germ cell regeneration in annelids.
Art the Science is a website that features and supports SciArt. Duygu has been featured as a creator (of SciArt) this month. See her interview and artwork here.
Emma is giving a talk as a part of the new exciting NeMOC series.
Electroporation as a post-embryonic delivery tool for uncovering mechanisms of regeneration in Platynereis dumerilii
From David Stern: Join the New Model Organism Occasional Seminar Series (NeMOC-OSS). Informal virtual talks on successes and struggles in building tools. Register here.
We have a new publication in Science Advances, an amazing collaborative body of work lead by the teams of Eric Schmidt and Toto Olivera at University of Utah. We are thrilled to be a part of this cute (and dramatic!) story of aggressive mimicry in cone snails, and how they use pheromones to trick worms like Platynereis to eat them. All the worm experiments to test reproduction behavior by administering cone snail small molecules were carried out at our lab.
Link to the research article: Small-molecule mimicry hunting strategy in the imperial cone snail, Conus imperialis
And some fun popular science media coverage of this story:
Bilim Kadınları platformu Twitter’da bu hafta Duygu’ya yer veriyor. Eğer bu hesabı takip etmiyorsanız mutlaka takip etmenizi öneriyoruz.
ÖZPOLAT LAB at the Marine Biological Laboratory, Woods Hole, MA, USA is looking for a postdoc
We are looking for a post-doctoral researcher to work on our NIH-funded germline regeneration project in the marine annelid Platynereis dumerilii.
The project involves live-imaging germline formation and regeneration in the embryonic, larval and juvenile stages of the worms using advanced microscopy. MBL has excellent imaging resources including several light sheet systems, confocal and spinning disk microscope as a part of the new exciting imaging initiative. The post-doc will have the opportunity to interact and learn from our internal and external collaborators, and take advantage of MBL’s vibrant community during the summers.
The project also includes microinjections to establish transgenic lines for visualizing germ cells and combining the imaging results with single cell transcriptomics.
Some prior imaging experience (familiarity with one or more of the systems above) is preferable but not necessary. The successful candidate will get the necessary training in imaging. Familiarity with molecular cloning, RNA/DNA techniques is required. Experience with tissue transcriptomics or single cell RNAseq would be a plus.
We are a lab that supports diversity and inclusion! Candidates from minoritized backgrounds are strongly encouraged to apply.
Please get in touch with the PI, B. Duygu Özpolat (dozpolat [at] mbl.edu), for informal inquiries.
We are happy to welcome a new lab member, Anna, who is joining as a Research Assistant. Anna will be working on establishing transgenic Platynereis lines to study germ cell development. Anna received her B.S. in Marine Biology from University of Rhode Island in 2020.
On this week's podcast episode of #DivingDeeper, we're talking about science, nature, art...and worms with MBL scientist B. Duygu Özpolat . Headphone Listen now on Spotify & Apple Podcasts: http://linktr.ee/ShowMustGoShow
https://art-lab-presents-diving-deeper.simplecast.com/episodes/conversation-with-duygu-ozpolat
Labmızda yaptığımız çalışmalara dair genel bir fikir edinmek isterseniz EkoEvo Derneği ile yaptığımız bu sunum ve söyleşiyi izleyebilirsiniz. EkoEvo’ya ve Dilşad’a çok teşekkür ederiz.
Özet:
Çok hücreli canlılar, eşeyli üreyebilmek için embriyonun gelişimi sırasında üreme hücrelerini yapacak hücre hattını oluştururlar. Biyolojide genel olarak kabul edilen görüş, bu üreme hücresi öncüllerinin, vücudun kalanını inşa edecek somatik hücrelerden ayrı ve özel hücreler olduğudur. Öyle ki, eğer üreme hücre hattı zarar görür veya deneysel olarak (veya ameliyatla) vücuttan alınırsa, somatic hücreler üreme hücrelerinin yerine geçemez ve canlı kısırlaşır. Fakat, bu genel olarak kabul edilen görüşe ters düşecek şekilde pek çok canlı, üreme hücrelerini rejenere edebilme yeteneğine sahiptir. Bu seminerde soma-üreme gücresi (germ) ayrımının geçerliliğini inceleyeceğiz. Üreme hücrelerini rejenere edebilen canlıların, yaygın olarak kabul gören bu temel ilkeyi sorgulamamıza neden sebep olduğunu, ve üreme hücresi rejenerasyonunun sağlık, hücre programlaması, popülasyon genetiği ve evrime kadar varan etkilerinin neler olabileceğini tartışacağız.
If you work on Spiralians join us at Spiraliabase, a community of scientists sharing ideas and meeting virtually for lab meetings.
Duygu has been one of the organizers of the monthly Virtual Lab Meetings, and you can find the recordings of these meetings and sign up for the future meetings on the Spiraliabase website.
Also don’t forget to follow Spiraliabase on Twitter!
We welcome our new team member, Bria, who is a new Research Assistant at the Özpolat lab. She will work on germline regeneration in Platynereis. Bria graduated this past spring from Brown University with dual honors in biology and english nonfiction. Though she didn’t see the ocean until age 13, she's wanted to study marine organisms ever since she saw the episode “She sells seashells by the sea shore” from What’s New Scooby Doo. Bria first came to the MBL as a student researcher in Dr. Irina Arkhipova's lab, and she's thrilled to once again be part of the scientific community here!
We are sad to see her go, but so excited for her new adventures in graduate school in Europe! Goodbye Emily. You will be sorely missed.
We are thrilled to share the news that our lab is now funded by NIH NIGMS with a MIRA grant to study germline regeneration in Platynereis dumerilii using live imaging, transgenics, and single cell sequencing.
Tune back in for new job opportunities at the Özpolat lab!
Kate and Duygu will be visiting ASU for the Center for Biology and Society conversation series. Date: 22 January 2020. Join us for a conversation on Germline Regeneration.
We will be at the ASCB/EMBO meeting in Washington D.C. in December to hold a roundtable discussion on "Developing approaches for testing gene function in post-embryonic stages". Please join us and spread the word! Follow us on Twitter for updates.
